The speech made by Siobhain McDonagh, the Labour MP for Mitcham and Morden, in Westminster Hall on 6 January 2026.
I thank the hon. Member for Wokingham (Clive Jones) for organising this debate. My purpose is to find a cure for glioblastoma brain tumours, the biggest cancer killer of children and adults under 40, with a life expectancy from diagnosis of just nine months and a five-year survival rate of 5%. The only way to find a cure and improve outcomes for a cancer that has seen no improvement in 30 years is through drug trials.
In the absence of commercial or charitable glioblastoma drug trials, we launched our own trial in memory of my late sister, Margaret, in July last year. The trial is being run by Dr Paul Mulholland, Europe’s leading consultant on glioblastoma, who is based at University College London. It will include 16 newly diagnosed patients at University College hospital. This is a pre-surgery immunotherapy trial focused on patients who have received no prior treatment. The drug is given before surgery, allowing the immune system to attack the tumour before it is removed.
I am delighted to confirm that we have already recruited five patients and, while the trial remains at an early stage, we are encouraged by the early findings. This is only the start. This journey has proven extraordinarily difficult and has been possible only because of an alignment of factors that very few will ever encounter: access to one of Europe’s leading clinicians working from a major London teaching hospital, alongside a world-class university; a group of my sister’s friends who have campaigned tirelessly and raised more than £1 million in two years; and the engagement and backing of the Secretary of State for Health and Social Care to get the trial over the line.
Our ambition is to establish 10 such trials using 10 different immunotherapy drugs, but ultimately our ability to raise money will end. How can Dr Mulholland apply for funding to support the programme of trials using repurposed immunotherapy drugs? Can the Minister’s team provide a written explanation and a link setting out how a bid can be made to the NIHR to access those funds? It is a straight question, and I would welcome a straight answer.