Tag: Lord Clement-Jones

The below Parliamentary question was asked by Lord Clement-Jones on 2016-03-01.

To ask Her Majesty’s Government what types of commercial agreements NHS England and NICE will be required to consider as part of the conditional approval route in the new Cancer Drugs Fund.

Lord Prior of Brampton

NHS England has advised that it intends to publish new detailed standard operating procedures for the Cancer Drugs Fund (CDF) by June 2016. These will include any further general details concerning the nature of managed access agreements associated with a drug’s entry into the Fund.

The Accelerated Access Review (AAR) is actively engaging with NHS England to ensure alignment between the work of the review on speeding up access for National Health Service patients to innovative and cost effective new medicines and the CDF. The AAR is looking at the capability of the National Institute for Health and Care Excellence, NHS England and the Department to support innovative pathways for the assessment, adoption and reimbursement of treatments.

The below Parliamentary question was asked by Lord Clement-Jones on 2016-02-22.

To ask Her Majesty’s Government how many patients they expect to benefit from the latest cancer medicines as a result of the proposals for a revised Cancer Drugs Fund to be effective from 1 April.

Lord Prior of Brampton

We have made no such assessment.

NHS England and the National Institute for Health and Care Excellence (NICE) recently consulted on draft proposals for the future direction of the Cancer Drugs Fund (CDF). The consultation outlines a new system, fully integrated into the NICE appraisal process, where the CDF becomes a transitional fund – with clear criteria for entry and exit. The consultation closed on 11 February 2016.

NHS England has advised that the operational detail of the new scheme will be developed over the coming months, informed by detailed analysis and consideration of the consultation responses received. A new Standard Operating Procedure for the CDF will be published by June 2016. Any changes to the list of available treatments through the Fund as a result of the changes in model will be published in due course.

NHS England has advised that it is optimistic that a greater number of cancer drugs will be funded from baseline commissioning in the future as a consequence of more appropriate pricing arrangements proposed by pharmaceutical manufacturers and the new CDF being able to address issues as to longer term patient outcomes in order to give such drugs the chance of re-appraisal by NICE with greater certainty as to clinical and cost effectiveness.

The below Parliamentary question was asked by Lord Clement-Jones on 2016-03-01.

To ask Her Majesty’s Government what assessment they have made of NHS England’s and NICE’s capabilities in relation to the commercial negotiations between them and pharmaceutical manufacturers in respect of the conditional approval route under the new Cancer Drugs Fund.

Lord Prior of Brampton

NHS England’s Board agreed, on 25 February 2016, a way forward which will see the proposed new arrangements for the Cancer Drugs Fund (CDF) going live on 1 July 2016

We expect NHS England and the National Institute for Health and Care Excellence (NICE) to work together to ensure that both organisations have the necessary capability and capacity to implement these proposals, including the introduction of a conditional approval route.

The Accelerated Access Review (AAR) is actively engaging with NHS England to ensure alignment between the work of the review on speeding up access for NHS patients to innovative and cost effective new medicines and the CDF. The AAR is looking at the capability of NICE, NHS England and the Department to support innovative pathways for the assessment, adoption and reimbursement of treatments.

The below Parliamentary question was asked by Lord Clement-Jones on 2016-02-26.

To ask Her Majesty’s Government what assessment they have made of the impact of proposals that the pharmaceutical industry should pay entirely for overspends in the Cancer Drugs Fund on the number of medicines that the industry puts forward for possible inclusion in that Fund.

Lord Prior of Brampton

NHS England plans to invest in a new £340 million Cancer Drugs Fund (CDF) to provide early access to cancer drug indications. Under the new process, any drugs that receive either a draft recommendation for routine commissioning or, where uncertainty exists, a recommendation for use within the CDF, will receive interim funding from the CDF from the point of marketing authorisation.

This earlier access to cancer drugs will benefit both patients and the pharmaceutical industry and NHS England believes it is only fair that the pharmaceutical industry makes a contribution if any overspend occurs.

NHS England’s impact assessment will not be completed until the detailed outcomes from the current consultation on the future of the CDF are confirmed.

The below Parliamentary question was asked by Lord Clement-Jones on 2016-03-03.

To ask Her Majesty’s Government what analysis they have carried out of the average annual earnings for (1) men, (2) women, and (3) all individuals, aged between 22 and 24 inclusive who are in possession of a first degree and who are not in full-time education.

Lord Bridges of Headley

The information requested falls within the responsibility of the UK Statistics Authority. I have asked the Authority to reply.

The below Parliamentary question was asked by Lord Clement-Jones on 2016-02-24.

To ask Her Majesty’s Government when they expect a reimbursement decision on each of the drugs launched since June 2015 that were affected by the pause in listing new drugs on the Cancer Drugs Fund list.

Lord Prior of Brampton

Since June 2015, the National Institute for Health and Care Excellence (NICE) has published final technology appraisal guidance on the cancer drugs/indications listed in the following table.

Topic title	Final guidance publication
Melanoma (unresectable, metastatic) – pembrolizumab (after ipilimumab) [TA357]	October 2015
Melanoma (unresectable, metastatic, ipilimumab naive) – pembrolizumab [TA366]	November 2015
Multiple myeloma – panobinostat (post 1 prior therapy) [TA380]	January 2016
Melanoma (advanced, unresectable, metastatic) – nivolumab [TA384]	February 2016

NHS England has advised that it envisages, under the new arrangements for the Cancer Drugs Fund (CDF), that a greater number of cancer drugs will be funded from baseline commissioning. Under the new process, any drugs that receive either a draft recommendation for routine commissioning or, where uncertainty exists, a recommendation for use within the CDF, will receive interim funding from the CDF from the point of marketing authorisation.

NICE has advised that it is unable to provide a forecast as to when this will occur for technology appraisals published during the first year of the new CDF as this will depend on a number of factors including the value proposition put forward by manufacturers.

The below Parliamentary question was asked by Lord Clement-Jones on 2016-03-03.

To ask Her Majesty’s Government what are the average earnings for (1) men, (2) women, and (3) all individuals, aged between 22 and 24 inclusive who are in possession of a first degree and who are not in full-time education in (a) the North East, (b) the North West, (c) Yorkshire, (d) the East Midlands, (e) the West Midlands, (f) East Anglia, (g) London, (h) the South East, (i) the South West, (j) Wales, (k) Scotland, and (l) Northern Ireland.

Lord Bridges of Headley

The information requested falls within the responsibility of the UK Statistics Authority. I have asked the Authority to reply.

The below Parliamentary question was asked by Lord Clement-Jones on 2016-02-24.

To ask Her Majesty’s Government how many cancer medicines are expected to be given a conditional approval by the National Institute for Health and Care Excellence in the first year of operation of the Cancer Drugs Fund.

Lord Prior of Brampton

The National Institute for Health and Care Excellence has advised that it is unable to provide a forecast as the number of technology appraisals published during the first year of the new Cancer Drugs Fund (CDF) will depend on a number of factors including the value proposition put forward by manufacturers.

NHS England has advised that it envisages, under the new arrangements for the CDF, that a greater number of cancer drugs will be funded from baseline commissioning. This will be as a consequence of more appropriate pricing arrangements proposed by pharmaceutical manufacturers and better evidence being available through the Fund as to longer term patient outcomes.

The below Parliamentary question was asked by Lord Clement-Jones on 2016-03-03.

To ask Her Majesty’s Government what are the average earnings for (1) men, (2) women, and (3) all individuals, aged between 22 and 24 inclusive who are in possession of a first degree and who are not in full-time education in each of the 50 most populous cities in the UK.

Lord Bridges of Headley

The information requested falls within the responsibility of the UK Statistics Authority. I have asked the Authority to reply.

The below Parliamentary question was asked by Lord Clement-Jones on 2016-02-24.

To ask Her Majesty’s Government, under the new Cancer Drugs Fund, what steps will be taken to secure early patient access to cancer medicines with Promising Innovative Medicines designation that have successfully passed through the Medicines and Healthcare products Regulation Agency’s Early Access to Medicines Scheme.

Lord Prior of Brampton

NHS England has advised that, under the proposals considered and approved by NHS England’s Board on 25 February 2016, the new Cancer Drugs Fund will provide access at drug launch for drug/indications which have a draft National Institute for Health and Care Excellence recommendation for use including those drugs that have successfully been through the Early Access to Medicines Scheme.